| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10968765 | Vaccine | 2011 | 9 Pages |
Abstract
⺠Gram-negative bacteria shed outer membrane vesicles (OMV). ⺠We studied adjuvant activity of OMV with penta-acylated LPS that is less endotoxic. ⺠The OMV with penta-acylated LPS has adjuvant activity on T cell priming. ⺠The adjuvant activity depends on Toll-like receptor-4. ⺠The OMV with penta-acylated LPS activates dendritic cells efficiently.
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Authors
Dong Ho Lee, Sang-Hyun Kim, Wonseok Kang, Yoon Seok Choi, Sang-Ho Lee, Sang-Rae Lee, Sooseong You, Heung Kyu Lee, Kyu-Tae Chang, Eui-Cheol Shin,