| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10968806 | Vaccine | 2012 | 7 Pages |
Abstract
⺠We show the immunologic responses to a species-specific pneumococcal whole cell vaccine administered with aluminum hydroxide. ⺠Antibody elicited by the vaccine cross-reacts to a panel of clinical pneumococcal isolates of diverse MLST and serotypes. ⺠Immunization with this vaccine primes T cells to produce robust IL-17A responses to pneumococci regardless of serotype. ⺠This data suggest broad responses and provide further support for the clinical development of this vaccine.
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Authors
Kristin L. Moffitt, Puja Yadav, Daniel M. Weinberger, Porter W. Anderson, Richard Malley,