Article ID Journal Published Year Pages File Type
10968817 Vaccine 2012 4 Pages PDF
Abstract
► Sipuleucel-T is the first approved autologous cellular immunotherapy. ► It is manufactured from antigen presenting cells obtained via leukapheresis. ► Sipuleucel-T has prolonged survival in Phase 3 studies in men with prostate cancer. ► Sipuleucel-T elicits robust antigen-specific cellular and humoral immune responses. ► Adverse events were generally mild to moderate and resolved within 2 days.
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