Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10968952 | Vaccine | 2012 | 10 Pages |
Abstract
⺠Inhibition of p38 MAPK increases transduction efficiency of moDCs by AAV2 vectors. ⺠Mutagenesis of serine residues increases transduction efficiency of moDCs by AAV2. ⺠Transduction of moDCs by mutant AAV2 does not induce phenotypic changes in these cells. ⺠DCs transduced with mutant AAV2 encoding a human telomerase stimulates specific CTLs.
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Authors
George V. Aslanidi, Angela E. Rivers, Luis Ortiz, Lakshmanan Govindasamy, Chen Ling, Giridhara R. Jayandharan, Sergei Zolotukhin, Mavis Agbandje-McKenna, Arun Srivastava,