Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10968962 | Vaccine | 2012 | 10 Pages |
Abstract
⺠DNA vaccines expressing the HA gene of equine H3N8 influenza virus were generated. ⺠DNA vaccines elicit homologous and heterologous immune responses after 3 vaccinations. ⺠DNA vaccines protect against disease and viral replication following H3N8 challenge. ⺠Needle-free delivery is as efficient and effective as conventional needle/syringe. ⺠DNA vaccines are a safe, effective alternative for veterinary vaccines against flu.
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Authors
Alida Ault, Alyse M. Zajac, Wing-Pui Kong, J. Patrick Gorres, Michael Royals, Chih-Jen Wei, Saran Bao, Zhi-yong Yang, Stephanie E. Reedy, Tracy L. Sturgill, Allen E. Page, Jennifer Donofrio-Newman, Amanda A. Adams, Udeni B.R. Balasuriya,