| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10968964 | Vaccine | 2012 | 7 Pages |
Abstract
⺠rB/HPIV3 & rHPIV3-NB contain â¥1 internal gene from BPIV3 & HN & F genes from HPIV3. ⺠In phase I trials both vaccines induced antibody in HPIV3-naïve children. ⺠rB/HPIV3 was significantly more restricted in replication than rHPIV3-NB. ⺠rB/HPIV3 induced significantly higher HPIV3 antibody titers than rHPIV3-NB. ⺠rB/HPIV3 is the preferred candidate for further clinical development.
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Authors
Ruth A. Karron, Bhagvanji Thumar, Elizabeth Schappell, Sonja Surman, Brian R. Murphy, Peter L. Collins, Alexander C. Schmidt,