Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10969010 | Vaccine | 2012 | 10 Pages |
Abstract
⺠Splenocytes from BCG and naïve guinea pigs were used to study ferritin levels. ⺠Ferritin was suppressed in vaccine-derived cells after PPD stimulation. ⺠TNFα and NO were involved in ferritin suppression. ⺠Microarray revealed suppression of further iron-related genes after M. tuberculosis infection. ⺠The regulation of iron is an important mechanism induced by BCG-vaccination.
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Authors
R.E. Thom, M.J. Elmore, A. Williams, S.C. Andrews, F. Drobniewski, P.D. Marsh, J.A. Tree,