Article ID Journal Published Year Pages File Type
10969018 Vaccine 2012 7 Pages PDF
Abstract
► Optimized DNA can serve as an effective boost following a robust Ad5 vector prime. ► Ad5-prime DNA-boost improved challenge control following SIVmac251 challenge. ► Control of SIV correlated with the expansion of HLA-DR+ CD8+ effector T-cells.
Keywords
Related Topics
Life Sciences Immunology and Microbiology Immunology
Preview
An optimized SIV DNA vaccine can serve as a boost for Ad5 and provide partial protection from a high-dose SIVmac251 challenge
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