Article ID Journal Published Year Pages File Type
10969022 Vaccine 2012 8 Pages PDF
Abstract
► The Vibrio cholerae wzm gene was expressed in the Lactococcus lactis cytoplasmic membrane. ► The L. lactis-Wzm construct elicited substantial levels of IgG and sIgA. ► Challenge with V. cholerae O1 evoked severe diarrhoea in non-immunised group. ► No diarrhoea in either recombinant or non-recombinant L. lactis treated groups.
Keywords
Related Topics
Life Sciences Immunology and Microbiology Immunology
Preview
Oral vaccination with Lactococcus lactis expressing the Vibrio cholerae Wzm protein to enhance mucosal and systemic immunity
Authors
, , , ,