Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10969257 | Vaccine | 2012 | 7 Pages |
Abstract
⺠NK cells and CD8+ T-cells expand relatively late following pneumovirus infection. ⺠Memory CD8+ T-cells support type 1 skewing of pneumovirus-specific responses. ⺠Memory CD8+ T-cells prevent pneumovirus-induced immunopathology. ⺠CD8+ T-cell targeted immunization protects against pneumovirus-induced disease.
Keywords
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Immunology
Authors
Mary J.G. van Helden, Peter J.S. van Kooten, Cornelis P.J. Bekker, Andrea Gröne, David J. Topham, Andrew J. Easton, Claire J.P. Boog, Dirk H. Busch, Dietmar M.W. Zaiss, Alice J.A.M. Sijts,