Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10969271 | Vaccine | 2012 | 6 Pages |
Abstract
⺠Protective responses to a DNA vaccine were compared after 2 delivery methods. ⺠Brugia malayi abundant larval transcript-2 DNA was used as the vaccine candidate. ⺠Gene gun delivery of BmALT-2 DNA vaccine was optimized in this study. ⺠Findings show that gene gun delivery of BmALT-2 DNA elicits significant protection. ⺠Gene gun approach required only 20 fold less DNA compared to intradermal approach.
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Authors
S.K. Joseph, S. Sambanthamoorthy, G. Dakshinamoorthy, G. Munirathinam, K. Ramaswamy,