Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10969295 | Vaccine | 2011 | 8 Pages |
Abstract
⺠Properties of chemically inactivated foot-and-mouth disease virus (FMDV) particles used for conventional vaccine production were characterized. ⺠Inactivated particles retained virion architecture and receptor binding properties. ⺠Inactivated particles were internalized into cells following an integrin dependent pathway. ⺠Inactivated particles were transported to early endosomes. ⺠Inactivated particles were transported to two different early endosome populations.
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Authors
Miguel A. MartÃn-Acebes, Ángela Vázquez-Calvo, Mónica González-Magaldi, Francisco Sobrino,