| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10969302 | Vaccine | 2011 | 9 Pages |
Abstract
⺠NS1N130A commonly reverted for the NS1130A/175A/207A virus in mice. ⺠Asparagine to serine/glutamine further attenuated the virus at the NS1130 site. ⺠Only NS1130-132QQA/175A/207A was highly attenuated in weanling and adult mice. ⺠Attenuated mutant viruses induced a protective immune response following lethal challenge.
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Authors
Melissa C. Whiteman, Jason A. Wicker, Richard M. Kinney, Claire Y.-H. Huang, Tom Solomon, Alan D.T. Barrett,