Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10969324 | Vaccine | 2011 | 5 Pages |
Abstract
A cross-sectional survey of measles seroprevalence in general population was conducted in Jiangsu province of China. Data were analyzed by employing commercial ELISA cut-offs and mixture models. The results suggest that the overall measles seroprevalence rate in Jiangsu province (88.7%, 95% confidence interval 87.7-89.6%) was lower than the level believed to be necessary for the elimination of measles. Mixture model could provide a more comprehensive understanding of these results by investigating the different levels of antibody response to vaccination or natural infection in the population, and suggest that the vaccine-induced antibody levels may wane with time. Additional actions should be conducted in the young adult cohorts aged 15-19 years in center region. SIAs for susceptible birth cohorts over the whole province are urgent.
Keywords
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Immunology and Microbiology
Immunology
Authors
Yuanbao Liu, Hong Tao, Fubao Ma, Peishan Lu, Ying Hu, Xiaoyan Ding, Pei Liu, Jie Min, Jingxin Li, Jinfang Sun, Shan Xiao,