Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10969366 | Vaccine | 2011 | 12 Pages |
Abstract
⺠Replacement of LAV NS1 gene for an NS1 gene that matches the target agent of a flavivirus chimera improves potency and efficacy. ⺠Effect appears to be mediated by positive effect of NS1 immunity. ⺠Reduced interference if vector is re-used.
Keywords
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Immunology
Authors
Tomohiro Ishikawa, Gongbo Wang, Douglas G. Widman, Ernesto Infante, Evandro R. Winkelmann, Nigel Bourne, Peter W. Mason,