| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10969427 | Vaccine | 2011 | 9 Pages |
Abstract
⺠A rapid method for VLP vaccine preparation comprising bacterial expression and in vitro self assembly is reported. ⺠Chimeric VLPs and capsomeres displaying antigen from Streptococcus and influenza are evaluated. ⺠VLPs induce high antibody response with no significant improvement due to adjuvant. ⺠Capsomeres are immunogenic and response is improved with adjuvant.
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Authors
Anton P.J. Middelberg, Tania Rivera-Hernandez, Nani Wibowo, Linda H.L. Lua, Yuanyuan Fan, Graham Magor, Cindy Chang, Yap P. Chuan, Michael F. Good, Michael R. Batzloff,