Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10969627 | Vaccine | 2012 | 7 Pages |
Abstract
⺠We used the LTR of the attenuated goat CAEV to express HIV genes in a DNA vaccine. ⺠This vaccine expresses efficiently all driven genes in transfected cells. ⺠This vaccine induces potent T cell responses in mice and macaques. ⺠This vaccine is safer since this LTR does not integrate with HIV integrase.
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Authors
Géraldine Arrode-Brusés, Ramakrishna Hegde, Yuhuai Jin, Zhengian Liu, Opendra Narayan, Yahia Chebloune,