| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10969730 | Vaccine | 2012 | 11 Pages |
Abstract
⺠Vaccine efficacy can be improved through systematic evaluation of optimal antigen combinations. ⺠Combining variable and well-conserved H5N1 antigens can improve DNA vaccine efficacy. ⺠Protection against divergent H5N1 viruses is achievable by mixing two different influenza antigens. ⺠The addition of three or more related and unrelated antigens reduces protection. ⺠Combining multiple antigens can be beneficial and detrimental.
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Authors
Ami Patel, Michael Gray, Yan Li, Darwyn Kobasa, Xiaojian Yao, Gary P. Kobinger,