Article ID Journal Published Year Pages File Type
10969731 Vaccine 2012 10 Pages PDF
Abstract
► Conserved PfRH5 High Activity Binding Peptides (HABPs) interact with RBC receptors. ► PfRH5 HABPs strongly inhibit in vitro merozoite invasion to RBCs. ► A single modification in the PfRH5 sequence modifies its specific binding to human RBCs.
Keywords
Related Topics
Life Sciences Immunology and Microbiology Immunology
Preview
A single amino acid change in the Plasmodium falciparum RH5 (PfRH5) human RBC binding sequence modifies its structure and determines species-specific binding activity
Authors
, , , , , ,