Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10969768 | Vaccine | 2011 | 11 Pages |
Abstract
⺠We evaluate the adjuvant effect of ArtinM and Jacalin in vaccination for neosporosis. ⺠Mice were immunized with Neospora antigen (NLA) associated or not with lectins. ⺠ArtinM increased NLA immunogenicity, IgG2a/IgG1 ratio, Th1 cytokine production. ⺠After challenge, ArtinM increased survival and decreased brain parasite burden. ⺠ArtinM showed stronger adjuvant effect than Jacalin in neosporosis vaccination.
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Authors
Mariana R.D. Cardoso, Caroline M. Mota, Dâmaso P. Ribeiro, Fernanda M. Santiago, Julianne V. Carvalho, Ester C.B. Araujo, Neide M. Silva, Tiago W.P. Mineo, Maria C. Roque-Barreira, José R. Mineo, Deise A.O. Silva,