Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10969830 | Vaccine | 2011 | 6 Pages |
Abstract
⺠GMDP peptide mimic, RVPPRYHAKISPMVN (RN-peptide) as a new non-pyrogenic adjuvant. ⺠Structure-activity relationship studies of shortened and Ala-scan analogues of RN-peptide. ⺠PRYH is ultimately required for binding to anti-GMDP-antibodies. ⺠RVPPRYH is a minimal peptide segment possessing adjuvant activity. ⺠Ala-scan approach revealed K9, I10, S11, Ð13 contributions into RN adjuvant activity.
Related Topics
Life Sciences
Immunology and Microbiology
Immunology
Authors
A.G. Laman, A.O. Shepelyakovskaya, Kh.M. Boziev, G.V. Savinov, L.K. Baidakova, A.N. Chulin, I.A. Chulina, T. Korpela, V.A. Nesmeyanov, F.A. Brovko,