Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10969839 | Vaccine | 2011 | 8 Pages |
Abstract
⺠We have developed a reservoir-targeted baited vaccine against Lyme disease. ⺠The vaccine is stable in oral baits under various environment-simulated conditions. ⺠A single dose of vaccine protects Peromyscus mice against infected tick bites. ⺠A single dose vaccine protects ticks from infection during feeding on carrier mice. ⺠Live, in vivo imaging was used to optimize bait composition.
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Authors
Debaditya Bhattacharya, Mekki Bensaci, Kathryn E. Luker, Gary Luker, Steven Wisdom, Sam R. Telford, Linden T. Hu,