| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10970369 | Vaccine | 2009 | 8 Pages |
Abstract
The live attenuated H5N1 VN 2004 and HK 2003 AA ca vaccines bearing avian H5 HA antigens were very restricted in replication and were more attenuated than seasonal LAIV bearing human H1, H3 or B HA antigens. The H5N1 AA ca LAIV elicited serum ELISA antibody but not HI or neutralizing antibody responses in healthy adults. (ClinicalTrials.gov Identifiers: NCT00347672 and NCT00488046).
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Authors
Ruth A. Karron, Kawsar Talaat, Catherine Luke, Karen Callahan, Bhagvanji Thumar, Susan DiLorenzo, Josephine McAuliffe, Elizabeth Schappell, Amorsolo Suguitan, Kimberly Mills, Grace Chen, Elaine Lamirande, Kathleen Coelingh, Hong Jin, Brian R. Murphy,