| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10971462 | Developmental & Comparative Immunology | 2014 | 14 Pages |
Abstract
- A C1 inhibitor gene (OfC1Inh) with conserved serpin family features was identified.
- The ORF of OfC1Inh was distributed within 10Â exons and promoter region of OfC1Inh was analyzed.
- Although OfC1Inh was constitutively transcribed, liver had extremely high number of transcripts.
- Modulated OfC1Inh transcription upon challenges showed its association with immunity.
- Purified (r)OfC1Inh showed inhibitory activity against mammalian C1 esterase and thrombin.
Keywords
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Authors
Navaneethaiyer Umasuthan, S.D.N.K. Bathige, Kasthuri Saranya Revathy, W.D.N. Wickramaarachchi, Qiang Wan, Ilson Whang, Eunmi Kim, Myoung-Ae Park, Hae-Chul Park, Jehee Lee,