Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10971641 | Developmental & Comparative Immunology | 2012 | 10 Pages |
Abstract
⺠First comprehensive study of gut-associated macrophages (hemocytes) in Drosophila. ⺠Gut-hemocytes are functional phagocytes recruited over development. ⺠Gut-hemocyte population size is regulated by PI3K. ⺠PI3K correspondingly regulates hemocyte adhesiveness and morphology. ⺠This regulation by PI3K shows surprising similarity to mouse models of colitis.
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Authors
Anna Zaidman-Rémy, Jennifer C. Regan, Ana Sofia Brandão, Antonio Jacinto,