| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10971643 | Developmental & Comparative Immunology | 2012 | 8 Pages |
Abstract
⺠Molecular characterisation of RIG-I-like helicases in the fruit bat Pteropus alecto. ⺠Bat RLHs are structurally conserved with those in other vertebrates. ⺠Bat RLHs are ubiquitously expressed and enriched in immune tissues. ⺠Treatment of bat kidney cells with poly I:C produces an fibroblast-like IFN response. ⺠Poly I:C induces upregulation of bat RLHs, indicating they are also ISGs.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Developmental Biology
Authors
Christopher Cowled, Michelle L. Baker, Peng Zhou, Mary Tachedjian, Lin-Fa Wang,