Article ID Journal Published Year Pages File Type
10971645 Developmental & Comparative Immunology 2012 8 Pages PDF
Abstract
► The gene encoding nucleotide-binding oligomerization domain 1 (NOD1) was cloned in olive flounder. ► NOD1 was expressed in all fish tissues examined. ► NOD1 mRNA levels was elevated in fish infected with Edwardsiella tarda, Streptococcus iniae, or VHSV. ► The inhibition of E. tarda and the increase of IL-1β levels were observed in NOD1 over-expressing cells.
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