| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10971648 | Developmental & Comparative Immunology | 2012 | 11 Pages |
Abstract
⺠We cloned BAFF from a cartilaginous fish, the spiny dogfish (Squalus acanthias). ⺠It is expressed as a type II transmembrane protein with a furin cleavage site. ⺠Cartilaginous fish BAFF has an additional exon compared to that of other species. ⺠The exon encodes a 29 aa extension in the a-aⲠloop, near the receptor binding site. ⺠It is highly expressed in immune tissues in vivo and up-regulated by PWM in vitro.
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Authors
Ronggai Li, Helen Dooley, Tiehui Wang, Christopher J. Secombes, Steve Bird,