The expression of CD25, CD11b, SWC1, SWC7, MHC-II, and family of CD45 molecules can be used to characterize different stages of Î³Î´ T lymphocytes in pigs

Article ID	Journal	Published Year	Pages	File Type
10971650	Developmental & Comparative Immunology	2012	13 Pages	PDF

Abstract

âº Porcine Î³Î´ T cells can constitutively express CD25 and MHC-II molecules. âº The frequency of CD25+, CD11b+, SWC1+ and SWC7+ Î³Î´ T cells increases by stimulation. âº Diversified TCRÎ´ repertoire was found inside CD25+, CD11b+, SWC1â and CD45RAâ cells. âº Expression of all studied molecules except of SWC7 is dependent on age/colonization. âº Putative developmental and activation markers of porcine Î³Î´ T cells are identified.

Keywords

PBS γδ T-cells BAL IL-2 MHC-II Germ-free animals Phorbol-12-myristate-13-acetate MLN PMA interleukin 2 germ-free T cell development Lymphocyte subpopulations Phosphate buffered saline bronchoalveolar lavage bone marrow cell surface molecules Major histocompatibility complex class II mesenteric lymph nodes