Article ID Journal Published Year Pages File Type
10971651 Developmental & Comparative Immunology 2012 10 Pages PDF
Abstract
► CXCa_L1 and CXCL8_L2 are functional homologs of mammalian CXCL8 while CXCb is functional homolog of CXCL9-11. ► Carp CXCa_L1 and CXCL8_L2, but not CXCb stimulate phagocyte activation. ► CXCa_L1 and CXCL_L2, but not CXCb, induce strong neutrophil recruitment in vivo. ► Recombinant CXCa_L1 triggers intracellular calcium mobilization in granulocytes.
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