Article ID Journal Published Year Pages File Type
10971715 Developmental & Comparative Immunology 2012 5 Pages PDF
Abstract
► Elevation of antimicrobial peptides (AMPs) by miR-8 loss in non-immunized state. ► Ectopic melanization occurs in miR-8 null flies without immune challenge. ► Increase of Drosomycin in miR-8 null larva is fat body organ specific. ► Re-introduction of miR-8 into fat body rescues the systemic AMP alteration. ► miR-8 in fat body regulates systemic AMP homeostasis independently of PI3K.
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