Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10971715 | Developmental & Comparative Immunology | 2012 | 5 Pages |
Abstract
⺠Elevation of antimicrobial peptides (AMPs) by miR-8 loss in non-immunized state. ⺠Ectopic melanization occurs in miR-8 null flies without immune challenge. ⺠Increase of Drosomycin in miR-8 null larva is fat body organ specific. ⺠Re-introduction of miR-8 into fat body rescues the systemic AMP alteration. ⺠miR-8 in fat body regulates systemic AMP homeostasis independently of PI3K.
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Authors
In Kyou Choi, Seogang Hyun,