Article ID Journal Published Year Pages File Type
10971716 Developmental & Comparative Immunology 2012 10 Pages PDF
Abstract
► CsCXCe1 is phylogenetically distantly related to all known CXC chemokines. ► CsCXCe1 expression was high in immune organs and activated by pathogen infection. ► rCsCXCe1 was chemotactic for the lymphocytes in the PBL of tongue sole and turbot. ► Mutation of the two Cys residues in the CXC motif abolished the activity of rCsCXCe1. ► rCsCXCe1 enhanced the activation and immune response of PBL.
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