| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10971721 | Developmental & Comparative Immunology | 2012 | 8 Pages |
Abstract
⺠We have successfully expressed a viral protein on the surface of Saccharomyces yeast. ⺠This delivery system stimulates naïve T cells even when using macrophages by inducing a strong stimulation of the innate immune system. ⺠The proliferating T cells produce a mixed cytokine profile, potentially supporting the development of cellular and humeral immune responses. ⺠Differences in the immune/proliferative response can be seen using either live or dead yeast particles.
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Authors
Robert Patterson, Jessica Nerren, Michael Kogut, Pinar Court, Bernardo Villarreal-Ramos, Hans-Martin Seyfert, Paul Dalby, Dirk Werling,