| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10972501 | International Journal for Parasitology | 2014 | 13 Pages |
Abstract
- Ostertagia ostertagi has three distinctive macrophage migration inhibitory factor (MIF) transcripts (Oos-MIF).
- Oos-MIF-1.1 is localised to hypodermis/muscle, reproductive tract and intestine, but not cuticle.
- Oos-MIF-1 is present in all developmental stages of O. ostertagi.
- rOos-MIF-1.1 has tautomerase, glucocorticoid counter-regulating and macrophage migration inhibitory activities.
- rOos-MIF-1.1 binds to a human MIF receptor and is internalised by macrophages.
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Authors
Guanggang Qu, Raymond Fetterer, Lin Leng, Xin Du, Dante Zarlenga, Zhiqiang Shen, Wenyu Han, Richard Bucala, Wenbin Tuo,