Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10972557 | International Journal for Parasitology | 2014 | 13 Pages |
Abstract
- The development of a vaccine for Fasciola spp. in livestock is a challenge.
- Harnessing acquired immunity expressed by resistant livestock against fluke infection will inform vaccine development.
- Antibody-dependent cell-mediated cytotoxicity at the surface of juvenile/immature flukes is a host immune mechanism.
- Antigens on the surface tegument of young flukes represent prime candidates for a fluke vaccine.
- Type 1 immune response shortly after fluke infection is associated with resistance to infection in resistant sheep.
Related Topics
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Immunology and Microbiology
Parasitology
Authors
Hayley Toet, David M. Piedrafita, Terry W. Spithill,