| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10972557 | International Journal for Parasitology | 2014 | 13 Pages |
Abstract
- The development of a vaccine for Fasciola spp. in livestock is a challenge.
- Harnessing acquired immunity expressed by resistant livestock against fluke infection will inform vaccine development.
- Antibody-dependent cell-mediated cytotoxicity at the surface of juvenile/immature flukes is a host immune mechanism.
- Antigens on the surface tegument of young flukes represent prime candidates for a fluke vaccine.
- Type 1 immune response shortly after fluke infection is associated with resistance to infection in resistant sheep.
Related Topics
Life Sciences
Immunology and Microbiology
Parasitology
Authors
Hayley Toet, David M. Piedrafita, Terry W. Spithill,