| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10972626 | International Journal for Parasitology | 2012 | 6 Pages |
Abstract
⺠Breakthrough method for the scale-up of synchronous and asynchronous malaria blood stage cultures in wave bioreactor. ⺠Significant savings on both labour and material costs, and reduced likelihood of culture contamination. ⺠Method allows large scale isolation of various stages of intra-erythrocytic stages from single culture. ⺠Methods will allow high throughput screening of compound libraries using identical live parasites. ⺠Methods will allow development of live or dead cell vaccines under GMP compliant standards.
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Authors
John P. Dalton, Corine G. Demanga, Sarah J. Reiling, Juliane Wunderlich, Jenny W.L. Eng, Petra Rohrbach,