Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10972635 | International Journal for Parasitology | 2012 | 10 Pages |
Abstract
⺠A Trichostrongylus colubriformis-intestinal epithelial cell co-culture system was developed. ⺠Trichostrongylus colubriformis consumed epithelial cell contents during in vitro coculture. ⺠It was determined that motile T. colubriformis induced epithelial cell necrosis. ⺠Motile T. colubriformis also induced the expression and release of IL33 from cells. ⺠Hence host responses to T. colubriformis were triggered by epithelial cell death.
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Authors
Nicholas M. Andronicos, Jody McNally, Andrew C. Kotze, Peter W. Hunt, Aaron Ingham,