Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10972646 | International Journal for Parasitology | 2012 | 8 Pages |
Abstract
⺠Malaria transmission blocking candidates need to be prioritized to transfer the best to the field. ⺠SMFA analyses vary between laboratories and efficacy estimates are often underpowered and highly uncertain. ⺠The effectiveness of a TBI candidate to reduce mosquito infectivity depends on parasite exposure. ⺠We show that the relationship between oocyst prevalence and intensity is predictable. ⺠This will allow laboratory results to be extrapolated to different field situations.
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Authors
Thomas S. Churcher, Andrew M. Blagborough, Michael Delves, Chandra Ramakrishnan, Melissa C. Kapulu, Andrew R. Williams, Sumi Biswas, Dari F. Da, Anna Cohuet, Robert E. Sinden,