| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10972667 | International Journal for Parasitology | 2013 | 6 Pages |
Abstract
- Vaccines that prevent transmission of Plasmodium parasites from mosquitoes would help towards eradicating malaria.
- Most such transmission-blocking vaccines target parasite antigens expressed within the mosquito.
- A vaccine is described which induced antibodies against a regulatory component of the mosquito innate immune response.
- These antibodies reduce the intensity of Plasmodium berghei infection in mosquitoes.
- This may be a novel approach to malaria transmission-blocking vaccines.
Related Topics
Life Sciences
Immunology and Microbiology
Parasitology
Authors
Andrew R. Williams, Sara E. Zakutansky, Kazutoyo Miura, Matthew D.J. Dicks, Thomas S. Churcher, Kerry E. Jewell, Aisling M. Vaughan, Alison V. Turner, Melissa C. Kapulu, Kristin Michel, Carole A. Long, Robert E. Sinden, Adrian V.S. Hill, Simon J. Draper,