Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10972672 | International Journal for Parasitology | 2013 | 7 Pages |
Abstract
- Sera from Cryptosporidium parvum-infected individuals bound to multivalent Tn antigen glycopeptides.
- Glycopeptides of C. parvum antigens Cp17 and Cp40 were synthesised with different Tn valency.
- Varying lengths of repeating serine residues (Cp40) were synthesised.
- The site of glycosylation had a pronounced effect on reactivity.
- Sera from individuals infected with Toxoplasma or Plasmodium recognised C. parvum Tn glycopeptides.
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Authors
Jamie Heimburg-Molinaro, Jeffrey W. Priest, David Live, Geert-Jan Boons, Xuezheng Song, Richard D. Cummings, Jan R. Mead,