Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10972677 | International Journal for Parasitology | 2011 | 13 Pages |
Abstract
⺠Toxoplasma gondii protects host cells from granzyme B-induced apoptosis. ⺠T. gondii prevents cleavage of granzyme B substrates in host cells âº. Reduced granzyme B activity is not due to abnormal granzyme uptake or trafficking. ⺠T. gondii inhibits the activity of granzyme B delivered by cytotoxic lymphocytes.
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Authors
Tatsuya Yamada, Tadakimi Tomita, Louis M. Weiss, Amos Orlofsky,