Article ID Journal Published Year Pages File Type
10972711 International Journal for Parasitology 2012 6 Pages PDF
Abstract
► Current strategy for treatment of clinical disease relies on species- and stage-specific therapies guided by diagnosis. ► This strategy derives from two historic biases favouring management of malaria in travellers. ► Elimination therapy means attacking all species and stages regardless of diagnostic outcome or availability. ► Hemolytic toxicity of primaquine in G6PDd patients is the primary impediment to therapies for managing endemic malarias. ► A research agenda for optimising primaquine therapy when combined with modern antimalarials is needed.
Related Topics
Life Sciences Immunology and Microbiology Parasitology
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