| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10972712 | International Journal for Parasitology | 2012 | 8 Pages |
Abstract
⺠Plasmodium vivax Duffy binding protein (DBP) is a leading vaccine candidate for blood-stage P. vivax malaria. ⺠Naturally acquired anti-DBP antibodies are associated with protection. ⺠Polymorphisms in DBP region II (DBPII) may compromise vaccine efficacy. ⺠A DBPII vaccine needs to focus on an immune response to conserved functional epitopes. ⺠An ideal vaccine includes a multi-allele, subunit or immunogen devoid of variant epitopes.
Related Topics
Life Sciences
Immunology and Microbiology
Parasitology
Authors
Francis B. Ntumngia, Christopher L. King, John H. Adams,