| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 11002046 | Psychoneuroendocrinology | 2018 | 29 Pages |
Abstract
Lower plasma total and calculated free testosterone were associated with increased risk of developing dementia independent of relevant measured clinical and biochemical factors and was not explained due to differential mortality in those with lower testosterone levels. The association between low testosterone and dementia is biologically plausible but data on the role of testosterone treatment in preventing dementia is lacking and adequately powered trials in men at risk would be welcome.
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Authors
Andrew H. Ford, Bu B. Yeap, Leon Flicker, Graeme J. Hankey, S.A. Paul Chubb, Jonathan Golledge, Osvaldo P. Almeida,