N-acetylcysteine modified hyaluronic acid-paclitaxel conjugate for efficient oral chemotherapy through mucosal bioadhesion ability

Article ID	Journal	Published Year	Pages	File Type
11003134	Colloids and Surfaces B: Biointerfaces	2018	10 Pages	PDF

Keywords

NAC 3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide dicyclohexylcarbodiimide tmax DCC PTX DAPI SIF SGF MRT 4-dimethylaminopyridine MWCO MCF-7 IC50 DMAP CMC Cmax PBS FBS DMF DLS PDI 4',6-diamidino-2-phenylindole AUC MTT N-acetylcysteine N,N-dimethylformamide Sprague-Dawley Hyaluronic acid peak concentration Tem Taxol Gastrointestinal Peak time fetal bovine serum polydispersity index Simulated intestinal fluid simulated gastric fluid critical micelle concentration Oral bioavailability Phosphate buffered saline the area under the curve Mucoadhesion Mean residence time Transmission electron microscope PAS the half maximal inhibitory concentration Molecular weight Paclitaxel Dynamic Light Scattering Amphiphilic polymers molecular weight cut-off high performance liquid chromatography HPLC Coumarin 6

Related Topics

Physical Sciences and Engineering Chemical Engineering Colloid and Surface Chemistry

N-acetylcysteine modified hyaluronic acid-paclitaxel conjugate for efficient oral chemotherapy through mucosal bioadhesion ability

Authors

Xin Jin, Sajid Asghar, Mei Zhang, Zhipeng Chen, Lin Huang, Qineng Ping, Yanyu Xiao,