| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 11006258 | European Journal of Medicinal Chemistry | 2018 | 24 Pages |
Abstract
1bf shows better activity (IC50â¯=â¯4.56â¯Î¼M) than EPZ004777 (IC50â¯=â¯35.19â¯Î¼M). Intermediate 9a displays good activity (IC50â¯=â¯29.98â¯Î¼M) and acceptable cytotoxicity (CC50â¯>â¯200â¯Î¼M).147
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Authors
Zeyu Tao, Ruiyuan Cao, Yunzheng Yan, Guocheng Huang, Kai Lv, Wei Li, Yunhe Geng, Lei Zhao, Apeng Wang, Qinghao He, Jingjing Yang, Shiyong Fan, Menghao Huang, Huiyuan Guo, Wu Zhong, Mingliang Liu,