| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 11010561 | The Ocular Surface | 2018 | 7 Pages |
Abstract
Rosiglitazone induced cell cycle exit and upregulation of lipogenic gene expression leading to lipid accumulation in hMGEC. These effects were suppressed by PPARγ antagonist indicating that PPARγ signaling specifically directs lipogenesis in hMGEC. These findings suggest that PPARγ plays a critical role in meibocyte differentiation.
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Authors
Sun Woong Kim, Yilu Xie, Paul Q. Nguyen, Vickie T. Bui, Kelly Huynh, Jonathan S. Kang, Donald J. Brown, James V. Jester,