Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
11011735 | Food Chemistry | 2019 | 27 Pages |
Abstract
In this paper, we employed a direct analysis in real time (DART) ion source coupled to QTRAP mass spectrometry for the analysis of chloramphenicol (CAP) in honey. The accuracy of the DART-MS/MS method for the analysis of CAP in honey was evaluated by comparison with data generated by a validated HPLC-MS/MS method. The sample preparation procedure was optimized to obtain sensitive and accurate determination of trace CAP residue in honey at concentrations less than 1.0â¯Âµg/kg. The DART-MS/MS method offers faster analysis time, lower cost per analysis, and reduced matrix effects and simplicity compared to HPLC-MS/MS method. Fifty-two honey samples collected from a Chinese market were analyzed using two methods. The results of the two methods are in good agreement, suggesting DART-MS/MS as a potential technique for the direct detection of trace amounts of veterinary drugs in complex matrixes.
Related Topics
Physical Sciences and Engineering
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Authors
Xiu Qin Li, Hong Mei Li, Sen Xu, Yan Gao, Qing He Zhang, Yan Zhang, Meng Yu Feng,