Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
11012852 | Chinese Journal of Catalysis | 2018 | 9 Pages |
Abstract
A straightforward and efficient protocol for dearomatizing indoles is described. The reaction, catalyzed by an inexpensive Co(III)/Zn(II) catalyst, starts from conveniently accessible N-pyrimidinyl indoles and ene-yne ketones. Mild reaction conditions, high diastereoselectivity, a broad substrate scope, reasonable functional group tolerance, and reasonable to remarkable yields were observed.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Catalysis
Authors
Na Li, Junbiao Chang, Lingheng Kong, Shuangjing Wang, Dandan Wang, Miao Cheng, Xingwei Li,