Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
11013210 | Surgery | 2018 | 5 Pages |
Abstract
Parathyroid carcinomas tended to have immune-ignorant and immune-tolerant microenvironments within the neoplasm (immunotypes II and IV). Of the parathyroid carcinoma microenvironments, 17 had patterns of programmed death-ligand 1 and tumor-infiltrating lymphocytes expression (immunotype I), suggesting possible benefit from immunotherapy. In addition, both parathyroid carcinomas and parathyroid neoplasms expressed CD68+. Further exploration of these potential biomarkers as a target in cancer therapies is needed.
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Authors
Angelica MD, Pamela MD, Michelle D. MD, Roland L. MS, Callisia N. MD, Jeffrey E. MD, FACS, Naifa L. MD, Nancy D. MD, FACS,